02212cam a22003617a 4500020002500000020002200025082001700047100003000064245003500094250000800129260005800137300002300195500006200218500005500280500015400335500027800489505018800767520045500955650001701410650002601427650002901453650002801482650002701510650002501537650001401562650002001576650002001596654001301616856006901629942000701698952013001705999001501835 a9789241563499 (pbk.) a9241563494 (pbk.) a616.994bWHO aWorld Health Organization10aIPCS mode of action framework  aNil aGeneva, Switzerland bWorld Health Organizationc2007 aiv, 123 p. bill.  aCover title.: IPCS Harmonization Project Document (No. 4) a"IPCS International Programme on Chemical Safety." a"This project was conducted within the IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals"--P. [i]. a"Published under the joint sponsorship of the World Health Organization, the International Labour Organization and the United Nations Environment Programme, and produced within the framework of the Inter-Oganization Programme for the Sound Management of Chemicals"--P. [i].0 apt. 1. IPCS framework for analysing the relevance of a cancer mode of action for humans -- pt. 2. IPCS framework for analysing the relevance of a non-cancer mode of action for humans. aThe use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical reviews in toxicology. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description. 0aCarcinogens. 0aHazardous substances. 0aCarcinogenicity testing. 0aHealth risk assessment.22aCarcinogenicity Tests.22aHazardous Substances22aNeoplasms22aRisk Assessment22aRisk Management aOncology41uhttp://whqlibdoc.who.int/publications/2007/9789241563499_eng.pdf cBK 00104070aAIMSCLbAIMSCLc31 F-24d2015-10-09eSupplier/Invoice No./Datel0o616.994 WHOp8321r2024-04-19 00:00:00yBKzBK c8622d8622