TY - BOOK AU - World Health Organization TI - IPCS mode of action framework SN - 9789241563499 (pbk.) U1 - 616.994 PY - 2007/// CY - Geneva, Switzerland PB - World Health Organization KW - Carcinogens KW - Hazardous substances KW - Carcinogenicity testing KW - Health risk assessment KW - Carcinogenicity Tests KW - Hazardous Substances KW - Neoplasms KW - Risk Assessment KW - Risk Management KW - Oncology N1 - Cover title.: IPCS Harmonization Project Document (No. 4); "IPCS International Programme on Chemical Safety."; "This project was conducted within the IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals"--P. [i]; "Published under the joint sponsorship of the World Health Organization, the International Labour Organization and the United Nations Environment Programme, and produced within the framework of the Inter-Oganization Programme for the Sound Management of Chemicals"--P. [i]; pt. 1. IPCS framework for analysing the relevance of a cancer mode of action for humans -- pt. 2. IPCS framework for analysing the relevance of a non-cancer mode of action for humans N2 - The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical reviews in toxicology. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description UR - http://whqlibdoc.who.int/publications/2007/9789241563499_eng.pdf ER -