World Health Organization creator text Geneva, Switzerland World Health Organization 2007 Nil monographic iv, 123 p. ill. The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical reviews in toxicology. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description. pt. 1. IPCS framework for analysing the relevance of a cancer mode of action for humans -- pt. 2. IPCS framework for analysing the relevance of a non-cancer mode of action for humans. Cover title.: IPCS Harmonization Project Document (No. 4) "IPCS International Programme on Chemical Safety." "This project was conducted within the IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals"--P. [i]. "Published under the joint sponsorship of the World Health Organization, the International Labour Organization and the United Nations Environment Programme, and produced within the framework of the Inter-Oganization Programme for the Sound Management of Chemicals"--P. [i]. Carcinogens Hazardous substances Carcinogenicity testing Health risk assessment Carcinogenicity Tests Hazardous Substances Neoplasms Risk Assessment Risk Management 616.994 WHO 9789241563499 (pbk.) 9241563494 (pbk.) http://whqlibdoc.who.int/publications/2007/9789241563499_eng.pdf http://whqlibdoc.who.int/publications/2007/9789241563499_eng.pdf