00495cam a2200217 a 4500020001500000082001300015100001800028245001700046250000800063260003400071300001100105650001700116650001700133650002600150650001000176650001800186650002200204650001800226654001700244700001600261  a082471681700a615bKAR  aKarch, Fred E00aOrphan drugs  aNil  aNew YorkbMarcel Dekkerc1982  a210 p. 0aChemotherapy 0aOrphan drugs 0aPharmaceutical policy 2aDrugs 2aDrug industry 2aLegislation, Drug 2aPublic policy  aPharmacology1 aKarch, Fred