Introduction--global evolution of diabetes in children and adolescents / Martin Silink, Kaichi Kida, and Arlan L. Rosenbloom -- Diagnosis and classification of type 2 diabetes in childhood and adolescence / Arlan L. Rosenbloom and Martin Silink -- Type 2 diabetes in children and adolescents in North America / Giuseppina Imperatore, Desmond E. Williams, and Frank Vinicor -- Type 2 diabetes in children and adolescents in Asia / Kaichi Kida -- Childhood and adolescent obesity / Louise A. Baur and Elizabeth Denney-Wilson -- Insulin resistance and insulin secretion in childhood and adolescence : their role in type 2 diabetes in youth / Silva A. Arslanian -- In-utero undernutrition and glucose homeostasis later in life / Delphine Jaquet, Claire Lʹevy-Marchal, and Paul Czernichow -- Clinical manifestations of the metabolic syndrome and type 2 diabetes in childhood and adolescence / Jill Hamilton and Denis Daneman -- Treatment of type 2 diabetes / Susan A. Phillips and Kenneth L. Jones -- Long-term outcome of type 2 diabetes in adolescence / Yasuko Uchigata -- The genetics of type 2 diabetes, MODY, and other syndromes / William E. Winter.